G6PD Antibody - Cat. #: CSB-PA009121KA01HU

SKU: CSB-PA009121KA01HU

Size :100ul

Clone Number:

Aliases:G6PD antibody; G6PD_HUMAN antibody; G6PD1 antibody; G6pdx antibody; Glucose 6 phosphate 1 dehydrogenase antibody; Glucose 6 phosphate dehydrogenase antibody; Glucose 6 phosphate dehydrogenase, G6PD antibody; Glucose-6-phosphate 1-dehydrogenase antibody; MET19 antibody; POS10 antibody; Zwf1p antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P11413

Immunogen:Recombinant protein of Human G6PD

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:2000

Background:Glucose-6-phosphate dehydrogenase (G6PD) catalyses the first and rate-limiting step of the pentose phosphate pathway. The NADPH generated from this reaction is essential to protect cells from oxidative stress. Recent studies have shown that p53 interacts with G6PD and inhibits its activity, therefore suppressing glucose consumption through the pentose phosphate pathway. In cancer cells with p53 mutations, the increased glucose consumption is directed towards increased biosynthesis, which is critical for cancer cell proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Affinity purification

Conjugate:Non-conjugated

Buffer:Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:G6PD

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction