FMN2 antibody , Cat. # FNab03166

SKU: FNab03166

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis(By similarity). Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. Protects cells against apoptosis by protecting CDKN1A against degradation.

Immunogen:formin 2

Synonyms:FMN2, formin 2

Observed MW:195 kDa

Uniprot ID:Q9NZ56

Reactivity:Human, Mouse

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:50-1:500

Gene ID:56776

Research Area:Neuroscience, Signal Transduction, Developmental biology