FineTest®488 Anti-Mouse CD274/PD-L1 Antibody(10F.9G2)

SKU: F488-30030

Size: 50T

Target: Mouse CD274/PD

Form: liquid

Conjugation: FineTest®488

Conjugation Information: FineTest® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).

Purification: 0

Purity: 0

Host: Rat

Clonality: Monoclonal

Clone ID: 10F.9G2

Isotype: IgG2b, κ

Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

Immunogen: 0

Synonyms: B7-H1|PD-L1|Programmed cell death ligand 1|B7 homolog 1|B7-H|B7H1|PDL1|PDCD1L1|PDCD1LG1

Observed MW:

Uniprot ID: Q9EP73

Reactivity: Mouse

Tested Application: FC

Recommended dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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Gene ID: 60533

Research Area:

Catagory: Flow cytometry Antibodies