FineTest®488 Anti-Mouse CD172a/SIRPα Antibody(P84)

SKU: F488-30268

Size: 50T

Target: Mouse CD172a/SIRPα

Form: liquid

Conjugation: FineTest®488

Conjugation Information: FineTest® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).

Purification: 0

Purity: 0

Host: Rat

Clonality: Monoclonal

Clone ID: P84

Isotype: IgG1, κ

Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.

Immunogen: 0

Synonyms: BIT|CD172 antigen-like family member A|P84|PTPNS1|SHPS-1|SIRPα

Observed MW:

Uniprot ID: P97797

Reactivity: Mouse

Tested Application: FC

Recommended dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

image5:

Gene ID: 19261

Research Area:

Catagory: Flow cytometry Antibodies