FBXO32 Polyclonal Antibody

SKU: E-AB-19785

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: FBXO32

Target Synonym: 4833442G10Rik;AI430017;Atrogin 1 ;Atrogin-1;ATROGIN1;Atrophy gene 1;F box only protein 32;F-box only protein 32;F-box protein 32;FBX32;fbxo25;FBXO32;FLJ32424;MAFbx;MGC108443;MGC137646;MGC33610 ;Muscle atrophy F box;Muscle atrophy F box protein;Muscle atrophy F-box protein

Research Areas: Cell Biology;Stem Cells;Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q969P5

Accession:

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1.44 mg/mL

Immunogen: Synthetic peptide of human FBXO32

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:30-1:150

Calculated MW:

ObservedMW: