FBXO2 Antibody - Cat. #: CSB-PA892326ESR1HU

SKU: CSB-PA892326ESR1HU

Size :50ul

Clone Number:

Aliases:F box gene 1 antibody; F box only protein 2 antibody; F box protein 2 antibody; F box protein only 2 antibody; F-box only protein 2 antibody; FBG 1 antibody; FBG1 antibody; Fbs 1 antibody; Fbs1 antibody; Fbs2 antibody; FBX 2 antibody; FBX2 antibody; FBX2_HUMAN antibody; FBXO 2 antibody; FBXO2 antibody; Neural F box protein NFB42 antibody; Neural F-box protein; 42-KD; rat; homolog of antibody; NFB 42 antibody; NFB42 antibody; OCP1 antibody; organ of Corti protein 1 antibody; Prpl4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UK22

Immunogen:Recombinant Human F-box only protein 2 protein (1-296AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBXO2

Research Areas:Cell biology