FBXL21 Antibody, FITC conjugated - Cat. #: CSB-PA891953LC01HU

SKU: CSB-PA891953LC01HU

Size :50ug

Clone Number:

Aliases:F box and leucine rich repeat protein 21 antibody; F box and leucine rich repeat protein 3 pseudogene antibody; F box and leucine rich repeat protein 3B antibody; F box protein Fbl3b antibody; F box/LRR repeat protein 21 antibody; F box/LRR repeat protein 3B antibody; F-box and leucine-rich repeat protein 21 antibody; F-box and leucine-rich repeat protein 3B antibody; F-box/LRR-repeat protein 21 antibody; F-box/LRR-repeat protein 3B antibody; Fbl 21 antibody; FBL 3 antibody; FBL 3B antibody; Fbl21 antibody; FBL3 antibody; FBL3B antibody; FBXL 21 antibody; FBXL 3B antibody; FBXL 3P antibody; Fbxl21 antibody; FBXL3B antibody; FBXL3P antibody; FXL21_HUMAN antibody; MGC120237 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UKT6

Immunogen:Recombinant Human F-box/LRR-repeat protein 21 protein (78-137AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBXL21

Research Areas:Others