FBW1B Rabbit Polyclonal Antibody

SKU: BT-AP02642

Size:100μL

Background:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and| in addition to an F-box| contains multiple WD40 repeats. This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Research_area:Epigenetics and nuclear signaling; Signal transduction

Target_protein:FBXW11

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FBW1B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):59620

UniProt accession:Human: Q9UKB1; Mouse: Q5SRY7

Synonyms:FBW1B

GeneID:Human: 23291; Mouse: 103583