FAM107A Antibody, Biotin conjugated - Cat. #: CSB-PA007987LD01HU

SKU: CSB-PA007987LD01HU

Size :50ug

Clone Number:

Aliases:Down regulated in renal cell carcinoma 1 antibody; Down-regulated in renal cell carcinoma 1 antibody; Downregulated in renal cell carcinoma antibody; DRR1 antibody; F107A_HUMAN antibody; FAM107A antibody; Family with sequence similarity 107; member A antibody; FLJ30158 antibody; FLJ45473 antibody; Protein FAM107A antibody; Protein TU3A antibody; TU3A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95990

Immunogen:Recombinant Human Actin-associated protein FAM107A protein (1-144AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity). Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner (PubMed:20543869). Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner (PubMed:10564580, PubMed:28604741). May play a role in tumor development (PubMed:10564580).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FAM107A

Research Areas:Cancer; Cell biology