FABP2 Monoclonal Antibody

SKU: BT-MCA4799

Size:100μL

Background:The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.

Research_area:Cardiovascular, Signal transduction, Metabolism, Stem cells, Developmental biology

Target_protein:FABP2

applications:WB, IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:9A9B7B3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:FABP2

Immunogen:Purified recombinant fragment of human FABP2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):15kDa

UniProt accession:P12104

Synonyms:FABPI, I-FABP, MGC133132, FABP2

GeneID:2169