F7 Antibody - Cat. #: CSB-PA960978

SKU: CSB-PA960978

Size :50ul

Clone Number:

Aliases:coagulation factor VII (serum prothrombin conversion accelerator) antibody; Coagulation factor VII antibody; Eptacog alfa antibody; F7 antibody; FA7_HUMAN antibody; Factor VII antibody; Factor VII heavy chain antibody; Factor VII light chain antibody; FVII coagulation protein antibody; OTTHUMP00000018733 antibody; OTTHUMP00000018734 antibody; Proconvertin antibody; Serum prothrombin conversion accelerator antibody; SPCA antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P08709

Immunogen:Fusion protein of Human F7

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:15-1:50

Background:This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:F7

Research Areas:Cardiovascular