F2 Antibody - Cat. #: CSB-PA877573

SKU: CSB-PA877573

Size :50ul

Clone Number:

Aliases:coagulation factor II (thrombin) antibody; Coagulation factor II antibody; F2 antibody; Factor II antibody; Prepro coagulation factor II antibody; Prothrombin antibody; prothrombin B-chain antibody; PT antibody; RPRGL2 antibody; serine protease antibody; THPH1 antibody; THRB antibody; THRB_HUMAN antibody; Thrombin heavy chain antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P00734

Immunogen:Synthetic peptide of Human F2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:F2

Research Areas:Cardiovascular?Cell biology;Signal transduction