ERN1 Antibody, FITC conjugated - Cat. #: CSB-PA007795LC01HU

SKU: CSB-PA007795LC01HU

Size :50ug

Clone Number:

Aliases:Endoplasmic reticulum (ER) to nucleus signalling 1 antibody; Endoplasmic reticulum to nucleus signaling 1 antibody; Endoplasmic reticulum-to-nucleus signaling 1 antibody; Endoribonuclease antibody; ER to nucleus signaling 1 antibody; ERN 1 antibody; Ern1 antibody; ERN1_HUMAN antibody; hIRE 1p antibody; hIRE1p antibody; Inositol requiring 1 antibody; Inositol requiring 1, S. cerevisiae, homolog of antibody; Inositol requiring enzyme 1, S. cerevisiae, homolog of antibody; Inositol requiring protein 1 antibody; inositol-requiring enzyme 1 antibody; Inositol-requiring protein 1 antibody; IRE 1 antibody; IRE 1a antibody; IRE 1P antibody; Ire1 alpha antibody; Ire1-alpha antibody; IRE1a antibody; Ire1alpha antibody; IRE1P antibody; MGC163277 antibody; MGC163279 antibody; Protein kinase/endoribonuclease antibody; RGD1559716 antibody; Serine/threonine protein kinase/endoribonuclease IRE1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75460

Immunogen:Recombinant Human Serine/threonine-protein kinase/endoribonuclease IRE1 protein (493-561AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ERN1

Research Areas:Signal transduction