ENPP7 Antibody - Cat. #: CSB-PA994398

SKU: CSB-PA994398

Size :50ul

Clone Number:

Aliases:ALK SMase antibody; Alk-SMase antibody; Alkaline sphingomyelin phosphodiesterase antibody; E-NPP 7 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 7 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 antibody; ENPP7 antibody; ENPP7_HUMAN antibody; Intestinal alkaline sphingomyelinase antibody; NPP-7 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6UWV6

Immunogen:Synthetic peptide of Human ENPP7

Raised in:Rabbit

Species Reactivity:Human, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) also known as alkaline sphingomyelin phosphodiesterase (Alk-SMase) or intestinal alkaline sphingomyelinase is an enzyme that in humans is encoded by the ENPP7 gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ENPP7

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology