EMR2 rabbit pAb

SKU: ES5733

Size: 100μL

Source:Rabbit

Applications:WB;IF;ELISA

Reactivity:Human

Dilution:Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human EMR2. AA range:765-814

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):85kD

Human_gene_id:30817

Human_swiss_prot_no:Q9UHX3

Subcellular_location:Cell membrane ; Multi-pass membrane protein. Cell projection, ruffle membrane ; Multi-pass membrane protein. Localized at the leading edge of migrating cells. .

Other_name:EMR2; EGF-like module-containing mucin-like hormone receptor-like 2; EGF-like module receptor 2; CD antigen CD312

Background:This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012],