EGLN1 Antibody - Cat. #: CSB-PA958222

SKU: CSB-PA958222

Size :50ul

Clone Number:

Aliases:C1ORF12 antibody; Chromosome 1 Open Reading Frame 12 antibody; DKFZp761F179 antibody; ECYT 3 antibody; ECYT3 antibody; Egl 9 family hypoxia inducible factor 1 antibody; EGL 9 homolog of C. elegans 1 antibody; EGL nine (C.elegans) homolog 1 antibody; Egl nine homolog 1 (C. elegans) antibody; Egl nine homolog 1 antibody; Egl nine like protein 1 antibody; EGLN 1 antibody; Egln1 antibody; EGLN1_HUMAN antibody; HIF PH2 antibody; HIF Prolyl Hydroxylase 2 antibody; HIF-PH2 antibody; HIF-prolyl hydroxylase 2 antibody; HIFP4H 2 antibody; HIFPH2 antibody; HPH 2 antibody; HPH-2 antibody; HPH2 antibody; Hypoxia inducible factor prolyl hydroxylase 2 antibody; Hypoxia-inducible factor prolyl hydroxylase 2 antibody; ORF13 antibody; P4H2 antibody; PHD 2 antibody; PhD2 antibody; PNAS 118 antibody; PNAS 137 antibody; Prolyl Hydroxylase Domain Containing Protein 2 antibody; Prolyl hydroxylase domain-containing protein 2 antibody; Rat Homolog of SM20 antibody; SM 20 antibody; SM-20 antibody; SM20 antibody; Zinc finger MYND domain containing protein 6 antibody; ZMYND6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9GZT9

Immunogen:Fusion protein of Human EGLN1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50

Background:The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EGLN1

Research Areas:Epigenetics and Nuclear Signaling;Cancer?Cardiovascular;Metabolism