EDEM2 rabbit pAb

SKU: ES6755

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:Synthesized peptide derived from the C-terminal region of human EDEM2.

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:55741

Human_swiss_prot_no:Q9BV94

Subcellular_location:Endoplasmic reticulum lumen .

Other_name:EDEM2; C20orf31; C20orf49; ER degradation-enhancing alpha-mannosidase-like 2

Background:In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008],