DR5/TRAIL R2 Monoclonal Antibody

SKU: AN200049P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:TNFRSF10B

Target Synonym:UNQ;PRO;Death Receptor;TRAIL Receptor;TNF-Related Apoptosis-Inducing Ligand Receptor;TRICK;ZTNFR;TRAILR;TRAIL-R;KILLER/DR;CD262;DR5;KILLER;KILLER/DR5;TRAIL-R2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9;TNFRSF10B;Death Receptor 5;TNF-Related Apoptosis-Inducing Ligand Receptor 2;TRAIL Receptor 2;Tumor Necrosis Factor Receptor Superfamily Member 10B;UNQ160;PRO186;DR5;KILLER;TNFRSF10b

Research Areas:Cell Biology;Signal Transduction;Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:ICC/IF

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:11G5

UNIProt ID:O14763

Accession:

Background:DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.

Concentration:1 mg/mL

Immunogen:Recombinant Human DR5/TRAIL R2 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100;

Calculated MW:

ObservedMW: