DOT1L Polyclonal Antibody

SKU: BT-AP08595

Size:100μL

Background:The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.

Research_area:Epigenetics and nuclear signaling

Target_protein:DOT1L

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Histone-lysine N-methyltransferase, H3 lysine-79 specific

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q8TEK3

Synonyms:Histone-lysine N-methyltransferase, H3 lysine-79 specific ;EC 2.1.1.43;DOT1-like protein;Histone H3-K79 methyltransferase;H3-K79-HMTase;Lysine N-methyltransferase 4

GeneID:Human: 84444