DOCK1 Antibody - Cat. #: CSB-PA047488

SKU: CSB-PA047488

Size :100ul

Clone Number:

Aliases:180 kDa protein downstream of CRK antibody; Ced5 antibody; Dedicator of Cytokinesis 1 antibody; Dedicator of cytokinesis protein 1 antibody; DOCK 1 antibody; DOCK 180 antibody; DOCK1 antibody; DOCK1_HUMAN antibody; DOCK180 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14185

Immunogen:Synthesized peptide derived from internal of Human DOCK1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.

Hasegawa H., Mol. Cell. Biol. 16:1770-1776(1996).
Deloukas P., Nature 429:375-381(2004).
Matsuda M., J. Biol. Chem. 271:14468-14472(1996).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DOCK1

Research Areas:Cancer;Cell biology;Metabolism;Signal transduction