DnaseⅠPolyclonal Antibody

SKU: E-AB-40592

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DnaseⅠ

Target Synonym: Deoxyribonuclease-1; DNASE1; DNL1; DRNI

Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P24855

Accession:

Background: Deoxyribonuclease I (DNase I) is an endonuclease which is secreted to cleave DNA in the extracellular space down to an average of tetranucleotides with 5′ monophosphate and 3′ hydroxyl DNA ends . Both single-stranded DNA and double-stranded DNA are degraded by Dnase I. This nuclease appears to account for the major nucleolytic activity on DNA in serum and is responsible for the degradation of the majority of circulating DNA derived from apoptotic and necrotic cell death and from neutrophil extracellular traps. In addition to its role in the serum, it has been proposed as one of the deoxyribonucleases responsible for DNA fragmentation in the process of apoptosis.

Concentration: 1 mg/mL

Immunogen: Recombinant Human DnaseⅠ protein expressed by E.coli.

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:1000-2000

Calculated MW: 31kDa

ObservedMW: 31kDa