DNAJA1 antibody , Cat. # FNab02439

SKU: FNab02439

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).

Immunogen:DnaJ(Hsp40) homolog, subfamily A, member 1

Synonyms:DJ 2, DjA1, DnaJ protein homolog 2, DNAJ2, DNAJA1, hDJ 2, HDJ2, Heat shock 40 kDa protein 4, Heat shock protein J2, HSDJ, HSJ 2, HSJ2, HSPF4, Human DnaJ protein 2

Observed MW:45 kDa

Uniprot ID:P31689

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200

Gene ID:3301

Research Area:Metabolism, Developmental biology