DHRS2 Antibody - Cat. #: CSB-PA273664

SKU: CSB-PA273664

Size :100ul

Clone Number:

Aliases:DHRS2 antibody; SDR25C1 antibody; Dehydrogenase/reductase SDR family member 2 antibody; mitochondrial antibody; EC 1.1.1.- antibody; Dicarbonyl reductase HEP27 antibody; Protein D antibody; Short chain dehydrogenase/reductase family 25C member 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13268

Immunogen:Synthesized peptide derived from internal of Human DHRS2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

Gabrielli F., Eur. J. Biochem. 232:473-477(1995).
Pellegrini S., Biochim. Biophys. Acta 1574:215-222(2002).
Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DHRS2

Research Areas:Cancer;Metabolism;Signal transduction