DHH Antibody - Cat. #: CSB-PA901875

SKU: CSB-PA901875

Size :50ul

Clone Number:

Aliases:C78960 antibody; Desert hedgehog (Drosophila) homolog antibody; Desert hedgehog antibody; Desert hedgehog homolog (Drosophila) antibody; Desert hedgehog protein C-product antibody; Desert hedgehog protein precursor antibody; DHH antibody; DHH_HUMAN antibody; GDXYM antibody; HHG-3 antibody; Hira antibody; SRXY7 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43323

Immunogen:Synthetic peptide of Human DHH

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DHH

Research Areas:Stem cells