DFF45(Cleaved-Ser118) Rabbit Polyclonal Antibody

SKU: BT-AP02238

Size:100μL

Background:Inhibitor of the caspase-activated DNase (DFF40).|PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.|PTM:Phosphorylated upon DNA damage| probably by ATM or ATR.|Contains 1 CIDE-N domain.|subunit:Heterodimer of DFFA and DFFB.|

Research_area:Cancer; Cell biology; Epigenetics and nuclear signaling; Metabolism

Target_protein:DFFA

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DFF45

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):36410

UniProt accession:Human: O00273; Mouse: O54786

Synonyms:DFF45 ;Cleaved-Ser118; DNA fragmentation factor subunit alpha; DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD

GeneID:Human: 1676; Mouse: 13347