DEN1B Rabbit Polyclonal Antibody

SKU: BT-AP02219

Size:100μL

Background:Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family| such as DENND1B| function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus| connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson| 2010

Research_area:Cell biology

Target_protein:DENND1B

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DEN1B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):46860

UniProt accession:Human: Q6P3S1; Mouse: Q3U1T9

Synonyms:DEN1B

GeneID:Human: 163486; Mouse: 329260