DEF-3 rabbit pAb

SKU: ES4433

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human RBM6. AA range:991-1040

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):150kD

Human_gene_id:10180

Human_swiss_prot_no:P78332

Subcellular_location:Nucleus .

Other_name:RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3

Background:disease:Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines.,function:Specifically binds poly(G) RNA homopolymers in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 G-patch domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,tissue specificity:Ubiquitous in adults.,