DAD1 rabbit pAb

SKU: ES17025

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human; Mouse;Rat

Dilution:WB 1：500-2000

Immunogen:Synthesized peptide derived from human DAD1 AA range: 38-88

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:1603

Human_swiss_prot_no:P61803

Subcellular_location:Endoplasmic reticulum membrane; Multi-pass membrane protein .

Other_name:

Background:DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008],