CYP11B2 Polyclonal Antibody

SKU: E-AB-17738

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CYP11B2

Target Synonym: ALDOS;Aldosterone synthase;Aldosterone-synthesizing enzyme;C11B2;CYP11B2;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Cytochrome P450 11B2;Cytochrome P450 11B2; mitochondrial;mitochondrial;P-450Aldo;P-450C18;Steroid 18-hydroxylase

Research Areas: Cancer;Cardiovascular;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P19099

Accession:

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Concentration: 1 mg/mL

Immunogen: Synthetic peptide of human CYP11B2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:300

Calculated MW: 58 kDa

ObservedMW: Refer to figures