CYCS Polyclonal Antibody

SKU: E-AB-70033

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CYCS

Target Synonym:Cytochrome C; Somatic;CYC;Cytochrome C;THC4;HCS.

Research Areas:Cancer;Cell Biology;Cardiovascular;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P99999,P62898,P62897

Accession:

Background:Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

Concentration:1.5 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:500-1:1000;IF 1:200-1:800

Calculated MW:12kDa

ObservedMW:12kDa