CXXC5 antibody , Cat. # FNab02113

SKU: FNab02113

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells(By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions(4% oxygen), as well as normoxia conditions(20% oxygen)(PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ(PubMed:23303788).

Immunogen:CXXC finger 5

Synonyms:

Observed MW:35-40 kDa

Uniprot ID:Q7LFL8

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:51523

Research Area:Signal Transduction