CTNNA1 Polyclonal Antibody

SKU: E-AB-10207

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CTNNA1

Target Synonym: Alpha E-catenin;Cadherin associated protein 102kDa;Cadherin associated protein;Cadherin-associated protein;CAP 102;CAP102;Catenin (cadherin associated protein) alpha 1 102kDa;Catenin (cadherin associated protein);alpha 1;102kDa;Catenin alpha 1;Catenin alpha-1;CTNA1;CTNNA 1;Ctnna1;FLJ36832;FLJ52416;MDPT2;NY REN 13 antigen;OTTHUMP00000224141;OTTHUMP00000224147;Renal carcinoma antigen NY REN 13;Renal carcinoma antigen NY-REN-13

Research Areas: Cancer;Signal Transduction;Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P35221

Accession:

Background: Catenin alpha-1is aproteinthat in humans is encoded by theCTNNA1gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be mucHuman, Mouseore dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human CTNNA1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 100kDa

ObservedMW: