CREBBP Antibody, FITC conjugated - Cat. #: CSB-PA838805LC01HU

SKU: CSB-PA838805LC01HU

Size :50ug

Clone Number:

Aliases:CBP antibody; CBP_HUMAN antibody; CREB binding protein antibody; CREB-binding protein antibody; Crebbp antibody; Cyclic AMP responsive enhancer binding protein antibody; KAT3A antibody; RSTS antibody; RTS antibody; Rubinstein Taybi syndrome antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92793

Immunogen:Recombinant Human CREB-binding protein (2217-2442AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CREBBP

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism; Microbiology; Stem cells