COX17 Polyclonal Antibody

SKU: E-AB-53364

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:COX17

Target Synonym:COX 17;COX17;COX17 cytochrome c oxidase assembly homolog (S. cerevisiae);COX17 cytochrome c oxidase assembly homolog;COX17 homolog cytochrome c oxidase assembly protein;COX17;cytochrome c oxidase assembly protein cox17 homolog;Cytochrome c oxidase copper chaperone;Human homolog of yeast mitochondrial copper recruitment;MGC104397;MGC117386;OTTHUMP00000215284;OTTHUMP00000215285

Research Areas:Cancer;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q14061

Accession:

Background:Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.

Concentration:1.1 mg/mL

Immunogen:Synthetic peptide of human COX17

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:40-1:250

Calculated MW:

ObservedMW: