Collagen II (8F6) Mouse mAb

SKU: EM1372

Size: 100μL

Source:Mouse

Applications:IHC

Reactivity:Human, Mouse, Rat

Dilution:IHC 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):142kDa

Human_gene_id:1280

Human_swiss_prot_no:P02458

Subcellular_location:Secreted,extracellular space,extracellular matrix

Other_name:Alpha 1 type II collagen , AOM, Col2a1 antibody

Background:Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.