COL2A1 Monoclonal Antibody

SKU: BT-MCA2268

Size:100μL

Background:This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Research_area:Signal Transduction

Target_protein:COL2A1

applications:IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:7F2A11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:COL2A1

Immunogen:Purified recombinant fragment of human COL2A1 (AA: 1222-1487) expressed in mammalian.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):142kDa

UniProt accession:P02458

Synonyms:AOM, ANFH, SEDC, STL1, COL11A3

GeneID:1280