CNTF rabbit pAb

SKU: ES20782

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human;Rat;Mouse

Dilution:WB 1:500-1000

Immunogen:Synthetic Peptide of CNTF

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):30kD

Human_gene_id:1270

Human_swiss_prot_no:P26441

Subcellular_location:Cytoplasm.

Other_name:CNTF; Ciliary neurotrophic factor; CNTF

Background:The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010],