CLDN8 Antibody - Cat. #: CSB-PA982170

SKU: CSB-PA982170

Size :50ul

Clone Number:

Aliases:Claudin 8 antibody; Claudin-8 antibody; CLD8_HUMAN antibody; Cldn8 antibody; Epididymis secretory protein Li 79 antibody; HEL S 79 antibody; OTTHUMP00000101915 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P56748

Immunogen:Synthetic peptide of Human CLDN8

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CLDN8

Research Areas:Signal transduction