CLDN6 Monoclonal Antibody

SKU: BT-MCA2445

Size:100μL

Background:Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]

Research_area:Microbiology

Target_protein:CLDN6

applications:FCM

Reactivity:

Clonality:Monoclonal

Clone ID:8G5D2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CLDN6

Immunogen:Purified recombinant fragment of human CLDN6 (AA: extra(29-81) and extra(138-160)) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):23.3kDa

UniProt accession:P56747

Synonyms:CLDN6

GeneID:9074