CHRNA10 Antibody - Cat. #: CSB-PA289370

SKU: CSB-PA289370

Size :100ul

Clone Number:

Aliases:Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody; ACH10_HUMAN antibody; Alpha 10 nAChR antibody; Cholinergic receptor nicotinic alpha 10 antibody; Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody; Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody; CHRNA 10 antibody; CHRNA10 antibody; NACHR alpha 10 antibody; NACHR alpha-10 antibody; NACHRA10 antibody; Neuronal acetylcholine receptor protein subunit alpha 10 antibody; Neuronal acetylcholine receptor subunit alpha-10 antibody; Nicotinic acetylcholine receptor subunit alpha 10 antibody; Nicotinic acetylcholine receptor subunit alpha-10 antibody; OTTHUMP00000013620 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9GZZ6

Immunogen:Synthesized peptide derived from C-terminal of Human CHRNA10.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Sgard F., Mol. Pharmacol. 61:150-159(2002).
Lustig L.R., Genomics 73:272-283(2001).
Vandenberk I., Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CHRNA10

Research Areas:Neuroscience;Signal transduction