CHRM3 Monoclonal Antibody

SKU: BT-MCA4412

Size:100μL

Background:The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.

Research_area:Neuroscience

Target_protein:CHRM3

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4A6B7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CHRM3

Immunogen:Purified recombinant fragment of human CHRM3 (AA: extra mix) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):66kDa

UniProt accession:P20309

Synonyms:HM3, PBS, EGBRS

GeneID:1131