Chicken Parathyroid Hormone, PTH ELISA Kit

SKU: EA0027Ch

Size:96 Tests-1 Kit

Background:Parathyroid hormone (PTH), also called parathormone or parathyrin, is a hormone secreted by the parathyroid glands that regulates the serum calcium concentration through its effects on bone, kidney, and intestine. PTH is secreted primarily by the chief cells of the parathyroid glands. It is a polypeptide containing 84 amino acids, which is a prohormone. It has a molecular mass around 9500 Da. Its action is opposed by the hormone calcitonin. There are two types of PTH receptors. Parathyroid hormone 1 receptors, activated by the 34 N-terminal amino acids of PTH, are present at high levels on the cells of bone and kidney. Parathyroid hormone 2 receptors are present at high levels on the cells of central nervous system, pancreas, testes, and placenta. The half-life of PTH is about 4 minutes. Disorders that yield too little or too much PTH, such as hypoparathyroidism, hyperparathyroidism, and paraneoplastic syndromes can cause bone disease, hypocalcaemia, and hypercalcaemia.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:PTH

Reactivity:Chicken

Assay type:Competitive

Sensitivity:0.27ng/ml

Detection range:0.5 - 100ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Parathyroid hormone

Species:Chicken

Storage:2-8ºC

Assay time:2h 30m

UniProt accession:

MASS(Da):

GeneID:

Synonyms:parathyroid hormone 1;PTH;PTH1

Gene names:PTH

Standard solution:128ng/L