CENPA Antibody - Cat. #: CSB-PA097091

SKU: CSB-PA097091

Size :100ul

Clone Number:

Aliases:CENP A antibody; CENP-A antibody; cenpa antibody; CENPA_HUMAN antibody; Centromere autoantigen A antibody; Centromere protein A 17kDa antibody; Centromere protein A antibody; Histone H3 like centromeric protein A antibody; Histone H3-like centromeric protein A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P49450

Immunogen:Synthesized peptide derived from internal of Human CENPA.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).

Sullivan K.F., J. Cell Biol. 127:581-592(1994).
Hillier L.W., Nature 434:724-731(2005).
Shelby R.D., J. Cell Biol. 136:501-513(1997).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CENPA

Research Areas:Epigenetics and Nuclear Signaling