CDH17 Monoclonal Antibody

SKU: BT-MCA3903

Size:100μL

Background:This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Research_area:Signal Transduction

Target_protein:CDH17

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:7D10E1

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CDH17

Immunogen:Purified recombinant fragment of human CDH17 (AA: extra(600-707)) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):92.2kDa

UniProt accession:Q12864

Synonyms:HPT1, CDH16, HPT-1

GeneID:1015