CD74 Polyclonal Antibody

SKU: E-AB-40347

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CD74

Target Synonym: CD 74;CD74;CD74 antigen (invariant polypeptide of major histocompatibility complex;class II antigen-associated);CD74 antigen;CD74 molecule;CD74 molecule;major histocompatibility complex;class II invariant chain;CLIP;DHLAG;Gamma chain of class II antigens;HG2A;HLA class II histocompatibility antigen gamma chain;HLA DR antigens associated invariant chain;HLA DR gamma;HLA-DR antigens-associated invariant chain;HLA-DR-gamma;HLADG;HLADR antigens associated invariant chain;Ia antigen associated invariant chain;Ia antigen-associated invariant chain;Ia associated invariant chain;Ia gamma;Ii;Invariant polypeptide of major histocompatibility complex class II antigen associated;la-gamma;Major histocompatibility complex class II invariant chain;MHC HLA DR gamma chain;MHC HLA-DR gamma chain;p33;p35;Protein 41

Research Areas: Cancer;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P04233

Accession:

Background: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Concentration: 1 mg/mL

Immunogen: Recombinant Human HLA class II histocompatibility antigen gamma chain protein

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:500-1:1000;IHC 1:100-1:300

Calculated MW: 33,26,18 kDa

ObservedMW: 35 kDa