CD318 (phospho Tyr707) rabbit pAb

SKU: ES7202

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:Synthesized phospho-peptide around the phosphorylation site of human CD318 (phospho Tyr707)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):140,80kD

Human_gene_id:64866

Human_swiss_prot_no:Q9H5V8

Subcellular_location:[Isoform 1]: Cell membrane ; Single-pass membrane protein . Shedding may also lead to a soluble peptide.; [Isoform 3]: Secreted.

Other_name:CDCP1; TRASK; CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD antigen CD318

Background:This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013],