CD27 Monoclonal Antibody

SKU: BT-MCA4261

Size:100μL

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Research_area:Cancer, Immunology, Stem cells

Target_protein:CD27

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:3B6D3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD27

Immunogen:Purified recombinant fragment of human CD27 (AA: extra 20-144) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):29.1kDa

UniProt accession:P26842

Synonyms:T14, S152, Tp55, TNFRSF7, S152. LPFS2

GeneID:939