CD150 antibody(PE conjugated) , Cat. # FNab09790

SKU: FNab09790

Size:100ug

Purification:Protein G purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rat

Clonality:monoclonal

Clone ID:3B6

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies.

Immunogen:signaling lymphocytic activation molecule family member 1

Synonyms:CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906

Observed MW:11kd

Uniprot ID:Q9QUM4

Reactivity:Mouse

Tested Application:FC

Recommended dilution:1?10-1?50

Gene ID:

Research Area: