CCL17 rabbit pAb

SKU: ES17761

Size: 100μL

Source:Rabbit

Applications:WB; ELISA

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000, ELISA(peptide)1:5000-20000

Immunogen:Synthesized peptide derived from human CCL17 AA range: 21-70

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):10kD

Human_gene_id:6361

Human_swiss_prot_no:Q92583

Subcellular_location:Secreted.

Other_name:C-C motif chemokine 17 (CC chemokine TARC;Small-inducible cytokine A17;Thymus and activation-regulated chemokine)

Background:This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014],