CAV1 Antibody - Cat. #: CSB-PA870052

SKU: CSB-PA870052

Size :100ul

Clone Number:

Aliases:BSCL3 antibody; CAV antibody; CAV1 antibody; CAV1_HUMAN antibody; caveolae protein, 22 kD antibody; caveolin 1 alpha isoform antibody; caveolin 1 beta isoform antibody; Caveolin 1 caveolae protein 22kDa antibody; Caveolin-1 antibody; Caveolin1 antibody; cell growth-inhibiting protein 32 antibody; CGL3 antibody; LCCNS antibody; MSTP085 antibody; OTTHUMP00000025031 antibody; PPH3 antibody; VIP 21 antibody; VIP21 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q03135

Immunogen:Synthesized peptide derived from Human Caveolin-1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500

Background:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity By similarity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Wei Zhang, J. Biol. Chem., Jun 2000; 275: 20717.
Rosalia Mora, J. Biol. Chem., Sep 1999; 274: 25708.
Isabella Parolini, J. Biol. Chem., Sep 1999; 274: 25718.
Phuong U. Le, J. Biol. Chem., Jan 2002; 277: 3371 - 3379.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CAV1

Research Areas:Cancer?Cardiovascular;Tags & Cell Markers;Metabolism;Signal transduction